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My first answer is 'hell no' and that's not really true.
I think about reactions with non-fic more than with fic. With non-fic I definitely work harder to start with a hook. I used to use my father-in-law as a test audience, because he really could care less about much of anything I was writing - but if I could get him to want to read, I figured I was on the right track.
I use white space a lot and that's a conscious thing - it's about rhythm and impact, so in that regard I think of the audience as well.
Blogging - I often blog hoping to get a reaction. Which strikes me as obvious.
Fiction - for the most part, I don't think I look much past the trying to get the feel of what I'm writing down accurately, being true to the voices in my head (so to speak). Which is sometimes a problem, because (for example) I don't want to spell everything out for the reader, and during my experience being in a writers' group that caused some contention. Yes, I answer the questions later; no, I'm not going to tell you until I dang well want to.
(Side note: I don't generally like these prompts, but the last few have caught my interest. I'm sure they'll go back to asking about vampire baseball soon enough.)